Beilstein J. Org. Chem.2014,10, 1433–1444, doi:10.3762/bjoc.10.147
-carbohydrates, in particular multiarm PEGylation, is presented.
Keywords: bioavailability; carbohydrates; conjugates; glycoPEGylation; multivalent glycosystems; multivalentPEGylation; Introduction
In recent years, the modification of biotherapeutics by covalent conjugation with polyethyleneglycol (PEG) known
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Graphical Abstract
Figure 1:
Types of PEG utilized for derivatization of drugs and peptides.